vesicular glutamate transporter 1 (VGluT1, solute carrier family 17 member 7, brain-specific Na+-dependent inorganic phosphate cotransporter, SLC17A7, BNPI, VGLUT1)

Function

• mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells
• may also mediate the transport of inorganic phosphate

Structure

• belongs to the major facilitator superfamily Na+/anion cotransporter family, VGLUT subfamily

Compartment

• cytoplasmic vesicle, secretory vesicle
• synaptic vesicle membrane

Expression

• expressed in several regions of the brain including: amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen & temporal lobe

More general terms

• transmembrane 12 protein
• solute carrier family 17 (SLC17, SLC17A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5703
• OMIM: https://mirror.omim.org/entry/605208
• UniProt: http://www.uniprot.org/uniprot/Q9P2U7.html