CHRNA7-FAM7A fusion protein (D-10, CHRNA7-DR1)

Function

(see genetics below)

Structure

• belongs to the ligand-gated ionic channel (TC 1.A.9) family

Compartment

membrane

Expression

expressed in hippocampus

Genetics

• encoded by a hybrid gene resulting from duplication of exons 5-10 of CHRNA7 gene fused 3-prime to FAM7A gene (exons A through E),
• the CHRFAM7A gene is in opposite orientation to CHRNA7 gene
• not represented on every human chromosome 15
• not clear whether transcript is actually translated

More general terms

• transmembrane 5 protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q494W8.html