CHRNA7 (nicotinic receptor alpha-7) gene

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Introduction

A segmental duplication of chromosome 15 involving CHRNA7 & Fam7A is one of the few features distinguishing the human genome from the chimpanzee genome.[1][2]

More general terms

References

  1. 1.0 1.1 Riley B, Williamson M, Collier D, Wilkie H, Makoff A. A 3-Mb map of a large Segmental duplication overlapping the alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human 15q13-q14. Genomics. 2002 Feb;79(2):197-209. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11829490
  2. 2.0 2.1 Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour- Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM. Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15252450

Database