neurexin-3-beta; neurexin III-beta (NRXN3 KIAA0743)

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^[1]

Function

neuronal cell surface protein that may be involved in cell recognition & cell adhesion
cytoplasmic C-terminal region binds to CASK
binds to neuroligins NLGN1, NLGN2 & NLGN3

Structure

belongs to the neurexin family
contains 1 laminin G-like domain

Compartment

membrane Alternative promoter: yes

Alternative splicing

named isoforms=3

Expression

expressed abundantly in all brain regions without marked regional preference^[1]

More general terms

neurexin-3

References

↑ ^1.0 ^1.1 Ullrich B et al Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron 14:497 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7695896

Database

Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9369
OMIM: https://mirror.omim.org/entry/600567
UniProt: http://www.uniprot.org/uniprot/Q9HDB5.html

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