ligand of Numb-protein X 2 (numb-binding protein 2, PDZ domain-containing RING finger protein 1, LNX2, PDZRN1)

Function

• interacts with phosphotyrosine interaction domain of NUMB
• NPXY motif necessary but not sufficient for interaction with PID domain of NUMB

Structure

• contains 4 PDZ doamins (DHR domains)
• contains 1 RING-type zinc finger

More general terms

• ring finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N448.html