zinc finger protein DZIP1 (DAZ-interacting protein 1/2, DZIP1, DZIP, DZIP2, KIAA0996)

Function

• spermatogenesis via interaction with DAZ
• isoform 1 & isoform 2 interact with DAZ proteins
• componont of RNA-binding complex ES cells & germ cells (putative)

Structure

• contains 1 C2H2-type zinc finger

Compartment

• nucleus, cytoplasm
• colocalizes with DAZ & DAZL in primordial germ cells

Alternative splicing

named isoforms=3

Expression

• predominantly expressed in testis
  • expressed in mature germ cells & secondary spermatocytes
  • weakly or not expressed in primary spermatocytes
• expressed in fetal brain, adult oocytes, ovary
• expressed in ES cells

More general terms

• C2H2 type zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/608671
• UniProt: http://www.uniprot.org/uniprot/Q86YF9.html