PR domain zinc finger protein 10; PR domain-containing protein 10; tristanin (PRDM10, KIAA1231, PFM7, TRIS)

Function

• may be involved in transcriptional regulation
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• the SET domain is degenerated, suggesting that it has lost methyltransferase activity
• contains 10 C2H2-type Zn+2 fingers
• contains 1 SET domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=6

More general terms

• C2H2 type zinc finger protein
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56980
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:56980
• UniProt: http://www.uniprot.org/uniprot/Q9NQV6.html