zinc finger protein 383 (ZNF383)

Function

• transcriptional repressor
• suppresses transcriptional activities mediated by MAPK signaling pathways
• KRAB domain is responsible for the transcriptional repressor activity

Structure

• belongs to the krueppel C2H2-type zinc-finger protein family
• contains 11 C2H2-type zinc fingers
• contains 1 KRAB domain

Compartment

• nucleus, cytoplasm
• shuttling between the nucleus & cytoplasm (putative)

Expression

• expressed in skeletal muscle > heart, placenta, liver, pancreas

More general terms

• C2H2 type zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=163087
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:163087
• UniProt: http://www.uniprot.org/uniprot/Q8NA42.html