zinc finger protein 272; zinc finger protein 460; zinc finger protein HZF8 (ZNF460, ZNF272)

Function

• may be involved in transcriptional regulation
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the krueppel C2H2-type Zn+2-finger protein family
• contains 11 C2H2-type Zn+2 fingers
• contains 1 KRAB domain

Compartment

nucleus (probable)

Expression

• highest expression in pancreas & liver
• ubiquitously expressed at low levels

More general terms

• C2H2 type zinc finger protein
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10794
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10794
• OMIM: https://mirror.omim.org/entry/604755
• UniProt: http://www.uniprot.org/uniprot/Q14592.html