ADP-ribosylation factor-like protein 17; ADP-ribosylation factor 7 variant (ARL17, ARL17A, ARF1P2, ARL17B, PRO2667, ARL17P1)

Function

• GTP-binding protein
• activates ADP-ribosyltransferase (putative)
• role in protein trafficking
• may modulate vesicle budding & uncoating within the Golgi

Structure

• belongs to the small GTPase superfamily, Arf family

Compartment

Golgi (putative)

Alternative splicing

named isoforms=3

Pathology

• allosteric activator of the cholera toxin catalytic subunit

More general terms

• ADP-ribosylation factor-like protein (ARL)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51326
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=641522
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51326
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:641522
• UniProt: http://www.uniprot.org/uniprot/Q8IVW1.html