sry-box-5 protein; transcription factor SOX-5 (sox5)

Function

• binds specifically to the DNA sequence 5'-AACAAT-3'
• activates transcription of COL2A1 & AGC1 in vitro

Structure

contains 1 HMG box DNA-binding domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=4

More general terms

• sox protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6660
• UniProt: http://www.uniprot.org/uniprot/P35711.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6660