mutS protein homolog 4; hMSH4 (MSH4)

Function

• role in meiotic recombination
• required for reciprocal recombination & proper segregation of homologous chromosomes at meiosis
• heterooligomer of MSH4 & MSH5

Structure

belongs to the DNA mismatch repair mutS family

Expression

testis & ovary specific

More general terms

• mutS family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4438
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4438
• OMIM: https://mirror.omim.org/entry/602105
• UniProt: http://www.uniprot.org/uniprot/O15457.html