RNA-binding motif, single-stranded-interacting protein 1; single-stranded DNA-binding protein MSSP-1; suppressor of CDC2 with RNA-binding motif 2 (RBMS1, MSSP, MSSP1, SCR2)

Function

• single-stranded DNA binding protein
• interacts with region upstream of the C-myc gene
• binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'
• probably has a role in DNA replication

Structure

contains 2 RRM domain (RNA recognition motif)s

Compartment

nucleus

Alternative splicing

named isoforms=3

Expression

• highest amounts are found in placenta, lung & heart
• expressed at highest levels during the G1 to S phase transition of the cell cycle

More general terms

• single-stranded DNA-binding protein
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5937
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5937
• OMIM: https://mirror.omim.org/entry/602310
• UniProt: http://www.uniprot.org/uniprot/P29558.html