F-box/LRR-repeat protein 18 (F-box & leucine-rich repeat protein 18, FBXL18, FBL18)

Function

• substrate-recognition component of the SCF complex
• interacts with SKP1A & CUL1

Structure

• contains 1 F-box domain
• contains 3 LRR repeats (leucine-rich repeats)

Alternative splicing

named isoforms=4

More general terms

• F-box & leucine-rich repeat protein

Component of

• SCF-type E3 ligase complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q96ME1.html