F-box & leucine-rich repeat protein-3A (FBXL3A, F-box/LRR-repeat protein 3, F-box/LRR-repeat protein 3A, FBXL3, FBL3A, FBXL3A)

Function

• recognizes & binds to phosphorylated proteins & promotes their ubiquitination & degradation (putative)
• interacts with SKP1
• component of SKP1-cullin-F-box protein ligase complex (SCF complex)

Structure

• contains 1 F-box domain
• contains 4 LRR repeats (leucine-rich repeats)

Compartment

• nucleus, cytoplasm (predominantly nuclear)

Expression

widely expressed

More general terms

• F-box & leucine-rich repeat protein

Component of

• SCF-type E3 ligase complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26224
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26224
• OMIM: https://mirror.omim.org/entry/605653
• UniProt: http://www.uniprot.org/uniprot/Q9UKT7.html