F-box only protein 27; F-box/G-domain protein 5 (FBXO27, FBG5, FBX27)

Function

• substrate-recognition component of the SCF complex (putative)
• directly interacts with SKP1A & CUL1 (putative)

Structure

• contains 1 F-box domain
• contains 1 FBA (F-box associated) domain

Expression

• predominantly expressed in brain, heart & kidney
• expressed at lower levels in liver & lung

More general terms

• F-box only protein

Component of

• SCF-type E3 ligase complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=126433
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:126433
• OMIM: https://mirror.omim.org/entry/609099
• UniProt: http://www.uniprot.org/uniprot/Q8NI29.html