F-box only protein 22; F-box protein FBX22p44 (FBXO22, FBX22)

Function

• substrate-recognition component of the SCF complex (putative)
• directly interacts with SKP1A & CUL1 (putative)

Structure

contains 1 F-box domain

Alternative splicing

named isoforms=3

Expression

predominantly expressed in liver

More general terms

• F-box only protein

Component of

• SCF-type E3 ligase complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26263
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26263
• OMIM: https://mirror.omim.org/entry/609096
• UniProt: http://www.uniprot.org/uniprot/Q8NEZ5.html