somatostatin receptor 3; SS3R; SSR-28 (SSTR3)

Function

• receptor for somatostatin-14 & somatostatin-28
• coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase
• phosphorylation increases upon somatostatin binding (putative)

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

• cell membrane
• internalized into endoplasmic vesicles upon somatostatin- stimulation (putative)

Expression

brain, pituitary & pancreas

More general terms

• somatostatin receptor
• phosphoprotein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6753
• OMIM: https://mirror.omim.org/entry/182453
• UniProt: http://www.uniprot.org/uniprot/P32745.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6753