orexin receptor type 2; Ox2r; hypocretin receptor type 2 (HCRTR2)

Function

• nonselective, high-affinity receptor for both orexin-A & orexin-B neuropeptides

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane, transmembrane 7 protein

Expression

• upregulated by Sirt1 in dorsomedial hypothalamus & lateral hypothalamus

More general terms

• hypocretin receptor; orexin receptor (Hcrtr)
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3062
• OMIM: https://mirror.omim.org/entry/602393
• UniProt: http://www.uniprot.org/uniprot/O43614.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3062