tripartite motif-containing protein 9; RING finger protein 91 (TRIM9, KIAA0282, RNF91)

Function

• may act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation (putative)
• interacts with SNAP25 (putative)

Structure

• the coiled coil domain mediates the interaction with the N-terminal t-SNARE domain of SNAP25 (putative)
• belongs to the TRIM/RBCC family
• contains 2 B box-type Zn+2 fingers
• contains 1 B30.2/SPRY domain
• contains 1 COS domain
• contains 1 fibronectin F3 module
• contains 1 RING-type Zn+2 finger

Alternative splicing

named isoforms=3

Notes

• competing donor splice site, exon inclusion & intron retention may be involved

More general terms

• tripartite motif-containing protein (trim protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=114088
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:114088
• OMIM: https://mirror.omim.org/entry/606555
• UniProt: http://www.uniprot.org/uniprot/Q9C026.html