DNA replication licensing factor MCM4; CDC21 homolog; P1-CDC21 (MCM4 CDC21)

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Function

role in the control of DNA replication
forms a stable trimeric complex with p85MCM & p105MCM
protein BM28/Mcm2 is more loosely associate with the trimeric complex

Structure

belongs to the MCM family
contains 1 MCM domain

Compartment

nucleus (putative)

More general terms

References

↑ UniProt http://www.uniprot.org/uniprot/P33991.html
↑ Musahl C et al A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins. Eur J Biochem 230:1096 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7601140
↑ NIEHS-SNPs http://egp.gs.washington.edu/data/mcm4/

Database

UniProt: http://www.uniprot.org/uniprot/P33991.html
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4173
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4173
OMIM: https://mirror.omim.org/entry/602638

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