ATP-dependent RNA helicase DDX17; DEAD box protein 17; RNA-dependent helicase p72; DEAD box protein p72 (DDX17)

Function

• RNA-dependent ATPase activity
• ATP + H2O = ADP + phosphate
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the DEAD box helicase family, DDX5/DBP2 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus

Alternative splicing

named isoforms=4

Expression

ubiquitous

More general terms

• DEAD box ATP-dependent helicase
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10521
• OMIM: https://mirror.omim.org/entry/608469
• UniProt: http://www.uniprot.org/uniprot/Q92841.html