N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2 (NGalNAc-T2, beta-1,4-N-acetylgalactosaminyltransferase 3, Beta4GalNAc-T3, Beta4GalNAcT3, B4GALNT3)

Function

• transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans & probably O-linked glycans
• mediates N,N'-diacetyllactosediamine formation on gastric mucosa

Structure

• belongs to the chondroitin N-acetylgalactosaminyltransferase family

Compartment

• Golgi, Golgi membrane
• localizes to apical Golgi

Alternative splicing

named isoforms=2

Expression

• highly expressed in testis, colon & stomach
• weakly expressed in other tissues

More general terms

• beta-1,4-N-acetylgalactosaminyltransferase (B4GALNT)

Database

• UniProt: http://www.uniprot.org/uniprot/Q6L9W6.html