beta-1,4-galactosyltransferase 6; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6 (B4GALT6)

Function

• role in glycosylation
• biosynthesis of glycosphingolipids inhibited by EDTA (putative)
• protein modification; protein glycosylation

UDP-galactose + glucosylceramide => UDP + lactosylceramide

Cofactor: Mn+2 or Mg+2 or Ca+2 (putative)

Structure

belongs to the glycosyltransferase 7 family

Compartment

• Golgi stack membrane
• trans cisternae of Golgi stack

Expression

• expressed in brain & adrenal gland > liver, lung, colon & peripheral white blood cells

More general terms

• beta-1,4-galactosyltransferase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9331
• OMIM: https://mirror.omim.org/entry/604017
• UniProt: http://www.uniprot.org/uniprot/Q9UBX8.html