chromosomal translocation t11q23:17q21 (acute leukemia)
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Pathology
- a chromosomal translocation t(11;17)(q23;q21) involving MLLT6 with MLL/HRX is associated with acute leukemias
- the result is a rogue activator protein
More general terms
Additional terms
- acute leukemia
- mixed lineage leukemia translocated to 6 (MLLT6, ALL1 fused gene from chromosome 17, AF17)
- myeloid/lymphoid, or mixed lineage, leukemia (MLL) gene, TRX1 gene, trithorax homolog, HRX gene or ALL1 gene
References
- ↑ OMIM https://mirror.omim.org/entry/600328
- ↑ Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Genes/AF17.html