myeloid/lymphoid, or mixed lineage, leukemia (MLL) gene, TRX1 gene, trithorax homolog, HRX gene or ALL1 gene

Introduction

7q

Function

• gene for zinc-finger protein

Pathology

• involved in translocations forming fusion products involved in myeloid/lymphoid, or mixed lineage, leukemias
• chromosomal translocation in acute leukemia
  • t(11;16)(q23;p13.3) involving CBP & MLL

More general terms

• proto-oncogene

Database

• OMIM: https://mirror.omim.org/entry/159555
• OMIM: https://mirror.omim.org/entry/159556
• OMIM: https://mirror.omim.org/entry/159557
• OMIM: https://mirror.omim.org/entry/604498
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7974