protein AF-17 (mixed lineage leukemia translocated to 6, MLLT6, ALL1 fused gene from chromosome 17 protein, AF17)

Structure

• contains 2 PHD-type zinc fingers

Compartment

nucleus

Pathology

• a chromosomal translocation t(11;17)(q23;q21) involving MLLT6 with MLL/HRX is associated with acute leukemias
  • the result is a rogue activator protein

More general terms

• zinc finger protein
• nuclear protein

Database

• OMIM: https://mirror.omim.org/entry/600328
• UniProt: http://www.uniprot.org/uniprot/P55198.html