chromosomal translocation t(2;3)(q35;q21) (renal cell carcinoma)

Introduction

- chromosomal translocation t(2;3)(q35;q21) involving HSPBAP1 with the putative pseudogene DIRC3 is found in familial renal cell carcinoma 1

• results in hybrid mRNA encoding a truncated HSPBAP1 lacking 1st 36 amino acids

chromosomal translocation t(2;3)(q35;q21) involving DIRC2 is found in familial renal cell carcinoma 1 (RCC1)

More general terms

• chromosomal translocation