acute myelomonocytic leukemia/AML-M4Eos

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[1][2]

Introduction

Fusion protein: cbf-beta with smooth muscle myosin heavy chain. Increased eosinophils in bone marrow; Most favorable prognosis of all AMLs; propensity for CNS involvement.

More general terms

References

  1. ↑ Knowles. Neoplastic Hematopathology, Williams & Wilkins, 1992 pg 1330
  2. ↑ Liu et al, Fusion between transcription factor CBF beta/PEB2 beta and a myosin heavy chain in acute myeloid leukemia. Science 261:1041 1993 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8351518
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