attention

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Introduction

Ability to sustain focused thought on a particular stimulus or activity. Neural pathways from the reticular-activating system in the brainstem to the intralaminar nuclei of the thalamus to the cerebral cortex constitute the attentional matrix.[2] These pathways play a role in alertness, response to stimuli & directed attention. The prefrontal, posterior parietal & medial temporal cortex (bilaterally) are most involved in general attention; the right parietal cortex is dominant for spatially-directed attention. Acetylcholine, dopamine & serotonin are the most important neurotransmitters involved in attentional pathways. Brainstem neural pathways regulating sleep & arousal overlap with those for attention. Norepinephrine associated with projections of the locus ceruleus plays a role in vigilance or arousal.

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References

  1. Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision, DSM-IV, American Psychiatric Association, Washington DC, 1994
  2. 2.0 2.1 Mahler ME, In: Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 29-Oct 2, 2004