acetylcholine (Miochol, Pragmoline)

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Introduction

Neurochemistry: Neurotransmitter at muscarinic & nicotinic synapses. Choline uptake is rate-limiting in acetylcholine synthesis. Acetylcholine is always the neurotransmitter in the 1st synapse leaving the central nervous system.

Pharmacology

Ophthalmic agent:

Indications

Contraindications

Dosage

Powder kit for preparation of 1:100 & 2.8% mannitol (10 mg/mL) intraophthalmic solution. 20 mg (2 mL).

Pharmacokinetics

duration of action is about 10 minutes

Adverse effects

More general terms

Additional terms

References

  1. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  3. UniProt http://www.uniprot.org/uniprot/Q9GZV3.html

Database