chronic mucocutaneous candidiasis

Introduction

A syndrome of impaired cytokine production.

Pathology

• deficient production of IL-2
• deficient production of interferon-gamma

Clinical manifestations

• recurrent & treatment-resistant Candida albicans infections of the skin, nails & mucous membranes

Management

• long term remissions with a 'Candida-specific' transfer factor

More general terms

• cellular immune dysfunction
• mucocutaneous candidiasis (includes vulvovaginal candidiasis)
• chronic skin disease
• chronic infection (chronic infectious disease)

More specific terms

• familial candidiasis type 2
• familial candidiasis type 6
• familial chronic mucocutaneous candidiasis with thyroid disease (CMCT)

Additional terms

• Candida albicans
• cytokine