transcription elongation factor A

Introduction

Facilitates RNA polymerase 2 transcription elongation past template-encoded arresting sites. These arresting sites trap a some of the elongating RNA polymerase, resulting in block of transcription. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'terminus.

More general terms

• biochemistry

More specific terms

• transcription elongation factor A protein 2 (transcription elongation factor S-II protein 2, transcription elongation factor TFIIS.i, TCEA2 TFIIS.i)
• transcription elongation factor A protein 3 (transcription elongation factor S-II protein 3, transcription elongation factor TFIIS.h, TCEA3 TFIISH)

Additional terms

• RNA polymerase-2