cachexia
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Introduction
Also see: cachexia-anorexia syndrome.
Clinical manifestations
- progressive weight loss
- lipolysis
- loss of visceral & skeletal protein mass
Management
- artificial nutrition does not improve morbidity or mortality[2]
- olanzapine may improve appetite, weight & quality of life in patients with metastatic cancer[3]
- small meals of foods preferred by elderly at the end of life[4]
More general terms
More specific terms
References
- ↑ Bruera E, Neumann CM. Management of specific symptom complexes in patients receiving palliative care. CMAJ. 1998 Jun 30;158(13):1717-26. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/9676549 PMCID: PMC1229444 Free PMC article
- ↑ 2.0 2.1 Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022
- ↑ 3.0 3.1 Sandhya L et al. Randomized double-blind placebo-controlled study of olanzapine for chemotherapy- related anorexia in patients with locally advanced or metastatic gastric, hepatopancreaticobiliary, and lung cancer. J Clin Oncol 2023 May 10; 41:2617 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36977285 Clinical Trial. https://ascopubs.org/doi/10.1200/JCO.22.01997
Roeland EJ, Bohlke K, Baracos VE et al Cancer Cachexia: ASCO Guideline Rapid Recommendation Update. J Clin Oncol. 2023 Sep 1;41(25):4178-4179. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37467399 - ↑ 4.0 4.1 Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022