cachexia
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Introduction
Also see: cachexia-anorexia syndrome.
Clinical manifestations
- progressive weight loss
- lipolysis
- loss of visceral & skeletal protein mass
Management
- artificial nutrition does not improve morbidity or mortality[2]
- olanzapine may improve appetite, weight & quality of life in patients with metastatic cancer[3]
- small meals of foods preferred by elderly at the end of life[4]
- dietary counseling, referral to a registered dietitian*[2][5]
* How is this going to change management?
* Something other than small meals of preferrd foods?
More general terms
More specific terms
References
- ↑ Bruera E, Neumann CM. Management of specific symptom complexes in patients receiving palliative care. CMAJ. 1998 Jun 30;158(13):1717-26. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/9676549 PMCID: PMC1229444 Free PMC article
- ↑ Jump up to: 2.0 2.1 2.2 Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022
Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025 - ↑ Jump up to: 3.0 3.1 Sandhya L et al. Randomized double-blind placebo-controlled study of olanzapine for chemotherapy- related anorexia in patients with locally advanced or metastatic gastric, hepatopancreaticobiliary, and lung cancer. J Clin Oncol 2023 May 10; 41:2617 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36977285 Clinical Trial. https://ascopubs.org/doi/10.1200/JCO.22.01997
Roeland EJ, Bohlke K, Baracos VE et al Cancer Cachexia: ASCO Guideline Rapid Recommendation Update. J Clin Oncol. 2023 Sep 1;41(25):4178-4179. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37467399 - ↑ Jump up to: 4.0 4.1 Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022
- ↑ Jump up to: 5.0 5.1 Roeland EJ, Bohlke K, Baracos VE, et al. Management of cancer cachexia: ASCO guideline. J Clin Oncol. 2020;38:2438-2453. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32432946