stool transplantation
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Indications
- refractory pseudomembranous colitis*, repeatedly testing positive for C difficile enterotoxin A or enterotoxin B
* patients willing to accept stool transplantation if recommended by their physician[2]
Benefits: 80% cure rate
Procedure
- stool donors screened for hepatitis, syphilis, HIV & enteric infections
- pretreatment of patients with vancomycin & proton pump inhibitor
- 25 mL of normal stool homogenate instilled via nasogastric tube
Complications
- risk of infection
More general terms
References
- ↑ Journal Watch 23(8):63, 2003 Aas J et al, Recurrent Clostridium difficile colitis: case series involving 18 patients treated with donor stool administered via a nasogastric tube. Clin Infect Dis 36:580,2003 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12594638
- ↑ Jump up to: 2.0 2.1 Zipursky JS et al. Patient attitudes toward the use of fecal microbiota transplantation in the treatment of recurrent Clostridium difficile infection. Clin Infect Dis 2012 Dec 15; 55:1652 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22990849