testosterone & risk of Alzheimer's disease

Introduction

Study characteristics:

• 574 men, mean age 66 years
• not demented at baseline

Results:

• low baseline serum free testosterone* associated with increased risk of developing Alzheimer's disease during 19 years of followup

* baseline total serum testosterone NOT associated with increased risk of Alzheimer's disease

More general terms

• prospective cohort study; prospective study