congenital diaphragmatic hernia

Introduction

Herniation of abdominal contents into the thoracic cavity.

Pathology

• congenital defects in the structural integrity of the diaphragm
• pulmonary hypoplasia
• pulmonary hypertension
• often lethal

Genetics

• associated with defects in ZFPM2 gene

More general terms

• diaphragmatic hernia
• genetic syndrome (multisystem disorder)

Additional terms

• Morgagni foramen hernia (parasternal, retrosternal or foramen of Bochdalek hernia)