Kufor-Rakeb syndrome (Parkinson disease-9)

Pathology

• more widespread neurodegeneration than typical Parkinson's disease, including Parkinson's dementia

Genetics

• associated with defects in ATP13A2 gene

Clinical manifestations

• juvenile onset
• typical signs of Parkinson's disease
• dementia

More general terms

• genetic syndrome (multisystem disorder)
• Parkinson's disease (paralysis agitans, PD)

Database

• OMIM: https://mirror.omim.org/entry/606693