F13A deficiency

Pathology

• life-long bleeding tendency
• impaired wound healing
• spontaneous abortion in affected women

Genetics

• autosomal recessive
• associated with defects in F13A ( factor XIII A chain)

Clinical manifestations

• subcutaneous & intramuscular hematomas
• severe bleeding including intracranial hemorrhages may occur

More general terms

• factor XIII deficiency

Additional terms

• hemophilia A; factor VIII deficiency

Database

• OMIM: https://mirror.omim.org/entry/134570