adapalene (Differin gel)
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Indications
treatment of acne vulgaris Now OTC.[3]
Contraindications
Warnings:
- patients with sunburn should not use adapalene until full recovery
- do not apply to lips, eyes, mucous membranes
Dosage
- cleanse area prior to application
- allow skin to dry 20-30 minutes
- apply QHS in a thin film
Gel 0.1%
Patient instructions:
- minimize exposure to sunlight
- avoid washing face more than 2-3 times/day
- discontinue use temporarily if irritation occurs
- avoid using topical alcohol preparations during treatment
- wash hands thoroughly after application
Adverse effects
- common (> 10%)
- uncommon (< 1%)
- skin irritation, stinging sunburn, acne flares
Drug interactions
- concurrent use of any other topical agent that may cause local irritation may result in additive drying effect
More general terms
Component of
References
- ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- ↑ Kaiser Permanente Northern California Regional Drug Formulary, 1998
- ↑ 3.0 3.1 Brown T FDA Approves First OTC Retinoid (Differin Gel 0.1%) for Acne. Medscape. Jul 08, 2016 http://www.medscape.com/viewarticle/865918
FDA News Release. July 8, 2016 FDA approves Differin Gel 0.1% for over-the-counter use to treat acne. First retinoid approved for over-the-counter use. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm510362.htm