sulfabenzamide/sulfacetamide/sulfathiazole (Koro-Sulf, Sultrin, Triple Sulfa)

Introduction

Tradenames: Koro-Sulf, Sultrin.

Indications

• treatment of Haemophilus vaginalis vaginitis

Dosage

Adults:

• apply one applicatorful into vagina BID for 4-6 days
• decrease dosage to 1/4-1/2 applicatorful BID after 4-6 days

Cream: (vaginal): (82.5 g) sulfabenzamide 3.7% sulfacetamide 2.86% sulfathiazole 3.42%

Adverse effects

• common (> 10%)
  • local irritation, pruritus, urticaria
• uncommon (< 1%)
  • allergic reactions, Stevens-Johnson syndrome

More general terms

• antibiotic combination

Additional terms

• Gardnerella (Haemophilus) vaginalis

Components

• sulfabenzamide
• sulfacetamide (Sulfacet)
• sulfathiazole (norsulfazole)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=60896