paltusotine (Palsonify)

Indications

• treatment of adults with acromegaly

Dosage

• start: 40 mg once daily
• titrate to: 60 mg once daily after 2-4 weeks
• tablets 20 mg, 30 mg

Adverse effects

• diarrhea, abdominal pain, nausea, decreased appetite, sinus bradycardia, hyperglycemia, palpitations, gastroenteritis
• cholelithiasis, hypothyroidism, dysglycemia

Mechanism of action

• somatostatin receptor agonist

More general terms

• endocrine agent

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=134168328
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=139299805
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=139299823