desulfovibrio

Introduction

genus of Gram-negative sulfate-reducing bacteria

Epidemiology

• commonly found in aquatic environments abundant in organic material & in water saturated soils
• minor component of intestinal microbiome increased by high-fat diet in mice & perhaps humans & women with BMI > 24

Pathology

• high amounts of desulfovibrio bacteria have been associated with
  • inflammatory bowel disease
  • sepsis
  • Parkinson's disease
• increases plasma levels of leucine that in turn increases levels of myeloid-derived suppressor cells which suppress the immune system & allows tumours to grow.

More general terms

• Vibrionaceae