diffuse panbronchiolitis

Epidemiology

• East Asian populations

Clinical manifestations

• chronic productive cough
• dyspnea on exertion
• chronic sinusitis

Radiology

• chest X-ray
  • diffuse pulmonary nodules
  • hyperinflation
• chest CT
  • centrilobular nodules
  • dilation of distal bronchioles

Complications

• left untreated, progresses to bronchiectasis, respiratory failure & death.

Management

• low-dose, long-term macrolide therapy

More general terms

• bronchiolitis