Sister Mary Joseph's node/nodule

Etiology

• metastasis of a malignant cancer in the pelvis or abdomen
• metastatic gastrointestinal cancer

Pathology

• malignant metastatic umbilical nodule
• sign of advanced stage of malignancy

Clinical manifestations

• a palpable nodule bulging into the umbilicus
• may be painful to palpation

Radiology

• abdominal ultrasound

Differential diagnosis

• umbilical hernia
• infection (abscess)
• endometriosis

More general terms

• skin nodule