UBX1325
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Indications
- diabetic macular edema
- neovascular age-related macular degeneration[1]
Mechanism of action
- UBX1325 binds to Bcl-xL & selectively induces apoptosis in senescent cells[1]
- a single dose of UBX1325 improves visual acuity in patients with diabetic macular edema or neovascular age-related macular degeneration[1]
More general terms
References
- ↑ 1.0 1.1 1.2 1.3 Bankhead C 'Senolytic' Therapy Shows Promise in Neovascular Eye Disease. Clearing out dying cells, approach has implications far beyond ophthalmology. MedPage Today July 14, 2022 https://www.medpagetoday.com/meetingcoverage/asrs/99734