protein structure

From Aaushi
Jump to navigation Jump to search

Introduction

  • an artificial intelligence (AI) company owned by Google developed a program that predicts 3-dimensional protein structure from their amino acid sequence[1]
  • on July 22, 2021, the company published its prediction of the structures of nearly all ~20,000 human proteins[1]

More general terms

Additional terms

References

  1. 1.0 1.1 1.2 Tunyasuvunakool K, Adler J, Wu Z et al. Highly accurate protein structure prediction for the human proteome. Nature 2021 Jul 22; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34293799 https://www.nature.com/articles/s41586-021-03828-1
    Jumper J, Evans R, Pritzel A et al. Highly accurate protein structure prediction with AlphaFold. Nature 2021 Jul 15; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34265844 https://www.nature.com/articles/s41586-021-03819-2
    Callaway E. Deepmind's AI predicts structures for a vast trove of proteins. Nature 2021 Jul 29; 595:635. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34294928 https://www.nature.com/articles/d41586-021-02025-4
    The Editors. Artificial intelligence in structural biology is here to stay. Nature 2021 Jul 29; 595:625. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34316055 https://www.nature.com/articles/d41586-021-02037-0
  2. Komaroff AL Breakthrough Discovery in Protein Structure Prediction and the Promise of New Treatments. JAMA. Published online September 23, 2021. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34554183 https://jamanetwork.com/journals/jama/fullarticle/2784583