IL-6 receptor inhibitor

Clinical significance

• tocilizumab & sarilumab are monoclonal Ab against the IL-6 receptor
• itolizumab is an anti-CD6 monoclonal Ab that reduces plasma IL-6
• these 3 monoclonal Ab are used as IL-6 inhibitors for COVID-19

More general terms

• receptor antagonist
• anti-inflammatory agent

More specific terms

• sarilumab (Kevzara)
• tocilizumab; atlizumab (Actemra, RoActemra)

Additional terms

• IL-6 inhibitors for COVID-19
• interleukin-6 receptor
• interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; hybridoma growth factor; interferon beta-2; IFN-beta-2 (IL6, IFNB2)