avacopan

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Indications

* non-inferior to prednisone as adjunctive therapy

Dosage

  • 30 mg PO BID for 52 weeks

Adverse effects

* prophylactic therapy for Pneumocystis jirovecii indicated

Mechanism of action

More general terms

References

  1. Jayne DRW, Merkel PA, Schall TJ, Bekker P for the ADVOCATE Study Avacopan for the Treatment of ANCA-Associated Vasculitis N Engl J Med 2021; 384:599-609. Feb 18 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33596356 https://www.nejm.org/doi/full/10.1056/NEJMoa2023386

Database