risdiplam (Evrysdi)

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Indications

Contraindications

-pregnancy

Dosage

  • 5 mg PO QD
  • 0.2 mg/kg if < 2 years of age

60 mg of risdiplam powder for constitution to provide 0.75 mg/mL solution

Adverse effects

Mechanism of action

More general terms

References

  1. Johnson K Risdiplam Promising for Spinal Muscular Atrophy. Medscape - Mar 09, 2021. https://www.medscape.com/viewarticle/947139
  2. Baranello G, Darras BT, Day JW et al Risdiplam in Type 1 Spinal Muscular Atrophy N Engl J Med 2021; 384:915-923 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33626251 https://www.nejm.org/doi/full/10.1056/NEJMoa2009965
  3. Highlights of prescribing information Evrysdi (risdiplam) for oral solution https://www.gene.com/download/pdf/evrysdi_prescribing.pdf

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